Definition of Epispastic:

Vesicant (L. vesica, a blister) and Epispastics (Gr. upon, + to draw) are Irritants or Counter-irritants which produce much inflammation of the skin and effusion of serum between the epidermis and derma: cantharides, mezereum, iodine, rhus toxicodendron, glacial acetic acid, volatile oil of mustard, steam, boiling water, ammonia vapor [Culbreth1927, pg 46].

Epispastics are those which cause blisters when applied to the surface of the body, forming sloughs [Brown1878; Meyer1932].

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